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Excipients must be safe in the concentrations and doses to be administered (considering the target indications, for example, adult versus pediatric use) and acceptable for parenteral use from a safety and regulatory standpoint

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Additionally, rapid weight loss during the initial weeks elevates skin exposure and reduces insulation, amplifying cold sensitivity

The dosage of the Vitamin B12 tablets will be decided by your doctor based on your medical condition, your laboratory values and your response to the treatment

In one study from Israel, researchers compared this standard schedule with a slower increase that took 16 weeks to reach a 1 mg dose